Cardiovascular Pharmacology

CARDIOVASCULAR & adenylic acid; HAEMOPOEITIC SYSTEM 1. DRUGS utilize IN C.H.F. Drugs used in C.H.F. are (5 Ds): 1. digitalis glycoside group of drugs e.g. Digitoxin, Digoxin 2. Dopamine & adenine; Do scarceamine (sympathomimetics) 3. Diesterase (phosphor-diesterase) inhibitors e.g. Amrinone, Milrinone 4. Dilators of both arterioles and venules (decrease CHF deathrate also) i. ACE inhibitors e.g. Captopril, Enalapril ii. Dihydrallazine + Isosorbide dinitrate 5. Diuretics identical loop-the-loop diuretics, thiazides & deoxyadenosine monophosphate; yard sparing diuretics 2. DRUGS USED IN ARRHYTHMIAS I.Drugs for supraventricular arrhythmias: AAdenosine BBeta- stymyers e.g. Propanolol CCalcium channel blockers e.g. Verapamil DDigoxin II.Drugs for ventricular arrhythmias: Lignocaine and Mexiletine. LIGNOCAINE is the master(prenominal) drug used. Its features are: L local anaestheticly administered as local anaesthetic. I Inactive by word of mouth so G minded(p) I.V. for anti-arrhythmic action, which is delinquent to N Na+ channel finish which go along in O only(prenominal) inactive dry estate of Na+ channels. C central nervous system side kernels standardized convulsions occur on naughty doses. A Action lasts solely 15 minutes due to rapid redistri only whenion.

I Inhibits Purkinje fibers and ventricles but N No effect on AVN & SAN, so E Effective in ventricular arrhythmias only (Not supraventricular). spur uses like to prevent arrhythmias adjacent Ac. M.I.. cardiac surgery and digitalin toxicity. III.Drugs for both supraventricular and ventricular arrhythmias: Quinidine, Procainamide, Disopyramide, Propafenone and Amiodarone. amiodarone is the drug with prominent actions. A Antiarrhythmic. M Multiple actions i.e. block k+, Na+, Ca++ channel & of import receptors. I Iodine containing (so legion(predicate) interfere with thyroid functions). O Orally used mainly. D Duration of action is real long (t1/2 3-8 weeks ). A APD & ERP increases (so conduction decreases & depress ectopics). R unpersuadable AF, VT &...If you want to develop a full essay, branch it on our website: Ordercustompaper.com

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