Innate immunity in tuberculosis Essay Example | Topics and Well Written Essays - 3000 words

Innate freedom in tuberculosis - Essay Exampleof the body, and patients would just waste away with no effective intercession however, to date, this infectious disease can be successfully treated with antibiotics (Schiffman, 2008).Brill et al., (2001) reported that tuberculosis corpse to be the major health problem worldwide and because of the prevalence of human immunodeficiency virus (HIV), tuberculosis becomes more significant in the years to come in regions where there is an endemic case of intracellular mycobacterium tuberculosis pathogen (Brill et al., 2001).Todar (2008) stated that a human immune system is composed of two major subdivisions, that is to say (1) Innate or non- unique(predicate) immune system, and (2) adaptive or specific immune system. The primary or the firstly line of defence mechanism against invading organism is known as the innate or non specific immune system (Todar, 2008). This contains cellular and humoral portions by which the protective function s atomic number 18 carried out (Todar, 2008). Junqueira - Kipnis et al (2003) famous that with M. tuberculosis, the innate and adaptive immune systems contributes to the defense of the host.Van Crevel et al (2002) noted that the outcome of the infection depends greatly on the relationship between M. tuberculosis and the human host. Both the innate and adaptive defense mechanism is involved with respect to the host. Hence, mechanisms to circumvent and antagonise protective opposition have been developed by M. tuberculosis.The component of the innate immune response atomic number 18 formed by phagocytosis and subsequent IL -12 secretion that argon initiated in the absence of prior antigen exposure (Raja, 2004). Natural resistance - associated macrophage protein, neutrophils, natural killer cells, and many others are considered as the component of innate immunity. Raja added that the first line of defense in the innate immunity of M. tuberculosis is played by the plasma lysozyme an d other enzymes.Van Crevel et al (2002) noted that macrophages are main effector cells